2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B1244R
    Dimetridazole (Standard)
    		Inhibitor
    Dimetridazole (Standard) is the analytical standard of Dimetridazole. This product is intended for research and analytical applications. Dmetridazole (1,2-Dimethyl-5-nitroimidazole), a nitroimidazole-based antibiotic, combats protozoan infections.
    Dimetridazole (Standard)
  • HY-125084
    NEU617
    		Inhibitor
    NEU617 is an anti-parasite agent. NEU617 inhibits the proliferation for the HAT (human African trypanosomiasis) pathogen (EC50: 42 nM for Trypanosoma brucei, 1.8 μM for T. cruzi). NEU617 is a derivative of Lapatinib (HY-50898).
    NEU617
  • HY-B1548R
    Benznidazole (Standard)
    		Inhibitor
    Benznidazole (Standard) is the analytical standard of Benznidazole. This product is intended for research and analytical applications. Benznidazole (Ro 07-1051) is an antiparasitic medication, with an IC50 of 20.35 μM for Colombian T. cruzi strains, and has been used in the treatment of Chagas disease.
    Benznidazole (Standard)
  • HY-W046346
    D44
    		Inhibitor
    D44 is a Plasmodium FKBP35 inhibitor that selectively inhibits the FKBD35 PPIase activity, with PPIase IC50 values of 132 nM and 125 nM for Plasmodium falciparum and Plasmodium vivax, respectively. D44 exhibits antiplasmodium activity and can be used in research related to infectious diseases.
    D44
  • HY-17596R
    Closantel (Standard)
    		Inhibitor
    Closantel (Standard) is the analytical standard of Closantel. This product is intended for research and analytical applications. Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing.
    Closantel (Standard)
  • HY-173264
    SDH-IN-24
    		Inhibitor
    SDH-IN-24 (Compound 51) is an inhibitor of succinate dehydrogenase (SDH). The LC50 against the second-stage juveniles of Bursaphelenchus xylophilus (B. xylophilus) is 6.9 mg/L, and the IC50 for SDH is 15.0 μM. SDH-IN-24 exerts its nematicidal activity by inhibiting the activity of SDH to interfere with the energy metabolism of nematodes. Meanwhile, it inhibits the motility, feeding, and reproduction of nematodes, induces oxidative stress, reduces the protein content of nematodes, and impairs their antioxidant capacity. SDH-IN-24 can be used in the research related to anti-nematode fields.
    SDH-IN-24
  • HY-N14622
    Fudecalone
    		Inhibitor
    Fudecalone is found in the strain of Penicillum sp. FO-2030. Fudecalone completely inhibits Eimeria Tenella, a coccidius resistant to Monesin (HY-N4302).
    Fudecalone
  • HY-101397R
    Allopurinol riboside (Standard)
    		Inhibitor
    Cholic acid (Standard) is the analytical standard of Cholic acid. This product is intended for research and analytical applications. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active.
    Allopurinol riboside (Standard)
  • HY-168931
    CCOE-5
    		Inhibitor
    CCOE-5 is a chalcone compound with antiplasmodial activity, showing an IC50 of 1.4 μg/mL against P. falciparum (3D7), and an IC50 of less than 5 μg/mL against P. falciparum (INDO). CCOE-5 holds promise for research in the field of anti-infective therapies.
    CCOE-5
  • HY-124232
    BTG 502
    		Inhibitor
    BTG 502 is an alkylamide insecticide. BTG 502 can reduce sodium current and antagonize the effect of bat toxin (BTX) on cockroach sodium channels.
    BTG 502
  • HY-B0273AR
    Sulfadiazine sodium (Standard)
    		Inhibitor
    Sulfadiazine (sodium) (Standard) is the analytical standard of Sulfadiazine (sodium). This product is intended for research and analytical applications. Sulfadiazine sodium is a sulfonamide?antibiotic with antimalarial activity. Sulfadiazine can be used for toxoplasmosis research.
    Sulfadiazine sodium (Standard)
  • HY-16973S5
    Fluralaner-d2
    		Inhibitor
    Fluralaner-d2 (A1443-d2) is deuterium labeled Fluralaner. Fluralaner (INN) is a systemic insecticide and acaricide Fluralaner through potent blockage of GABA and L-glutamate gated chloride channels.
    Fluralaner-d<sub>2</sub>
  • HY-160675
    TCMDC-137332
    		Inhibitor
    TCMDC-137332 is a compound that exhibits antimalarial activity against Plasmodium falciparum with an IC50 value of 7 nM. TCMDC-137332 can be utilized for the research of malaria.
    TCMDC-137332
  • HY-12651S
    Primaquine-d3 diphosphate
    		Inhibitor
    Primaquine-d3 (diphosphate) is the deuterium labeled Primaquine diphosphate. Primaquine Diphosphate (Primaquine phosphate), an 8-aminoquinoline, exerts a broad spectrum of activities against various stages of parasitic malaria. Primaquine Diphosphate remains as the only agent that destroys late hepatic stages and latent tissue forms of Plasmodium vivax and Plasmodium ovale.
    Primaquine-d<sub>3</sub> diphosphate
  • HY-N14970
    Hexacyclinol
    		Inhibitor
    Hexacyclinol has moderate anti-Gram-positive bacteria activity, 4-40 μg/mL can inhibit the production of oxidants by polymorphonuclear neutrophils (PMNL) stimulated by zymosan. Hexacyclinol inhibits the growth of L-930 and K 562 cells with IC50s of 1.4 μg/mL and 0.4 μg/mL, respectively, and the IC50 of HeLa cells is 10 μg/mL. Hexacyclinol also has an anti-Plasmodium effect, and its IC50 for Plasmodium falciparum is 2.4 μg/mL.
    Hexacyclinol
  • HY-163833
    MMV1634566
    		Inhibitor
    MMV1634566 is a potent antimalarial agent. MMV1634566 inhibits Plasmodium falciparum. MMV1634566 shows cytotoxicity.
    MMV1634566
  • HY-A0130R
    Sulfalene (Standard)
    		Inhibitor
    Sulfalene (Standard) is the analytical standard of Sulfalene. This product is intended for research and analytical applications. Sulfalene (Sulfametopyrazine) is an antimalarial agent. Sulfalene is also a long-acting sulfonamide antibacterial.
    Sulfalene (Standard)
  • HY-B1221R
    Flufenamic acid (Standard)
    		Inhibitor
    Flufenamic acid (Standard) is the analytical standard of Flufenamic acid. This product is intended for research and analytical applications. Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase (COX), activates AMPK, and also modulates ion channels, blocking chloride channels and L-type Ca2+ channels, modulating non-selective cation channels (NSC), activating K+ channels. Flufenamic acid binds to the central pocket of TEAD2 YBD and inhibits both TEAD function and TEAD-YAP-dependent processes, such as cell migration and proliferation.
    Flufenamic acid (Standard)
  • HY-N15375
    Trichomycin B
    		Inhibitor
    Trichomycin B is a polyene macrolide antibiotic that can be isolated from the fermentation products of Streptomyces hachijoensis. Trichomycin B exhibits antibacterial activity against fungi, yeasts, and trichomonas. Trichomycin B can be used in research on antifungal and anti-trichomoniasis infection.
    Trichomycin B
  • HY-123305R
    5-Hydroxymebendazole (Standard)
    5-Hydroxymebendazole (Standard) is the analytical standard of 5-Hydroxymebendazole. This product is intended for research and analytical applications. 5-Hydroxymebendazole is the one metabolite of Benzimidazoles. Benzimidazoles are safe, broad-spectrum anthelmintic agents and are widely used for prevention and treatment of parasitic infections in food-producing animals.
    5-Hydroxymebendazole (Standard)
Parasite Isoform Comparison

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